Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #truncNotch_versus_absentNotch |
| Phenotype | phenotype_absentNotch_versus_truncNotch.cls#truncNotch_versus_absentNotch |
| Upregulated in class | absentNotch |
| GeneSet | NCI_HEDGEHOG SIGNALING EVENTS MEDIATED BY GLI PROTEINS |
| Enrichment Score (ES) | -0.6528832 |
| Normalized Enrichment Score (NES) | -1.6209632 |
| Nominal p-value | 0.006756757 |
| FDR q-value | 0.2777173 |
| FWER p-Value | 0.851 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | SUFU | 6650181 | 550 | 2.638 | 0.0218 | No | ||
| 2 | ARRB2 | 2060441 | 722 | 2.368 | 0.0587 | No | ||
| 3 | SIN3B | 6650253 | 2442 | 0.944 | -0.0155 | No | ||
| 4 | CSNK1D | 4280280 4480167 6450600 | 2575 | 0.866 | -0.0058 | No | ||
| 5 | RBBP4 | 6650528 | 2771 | 0.764 | -0.0014 | No | ||
| 6 | PRKACA | 2640731 4050048 | 3134 | 0.598 | -0.0092 | No | ||
| 7 | CSNK1G1 | 840082 1230575 3940647 | 3503 | 0.469 | -0.0199 | No | ||
| 8 | GNAZ | 6130296 | 4339 | 0.293 | -0.0592 | No | ||
| 9 | SMO | 5340538 6350132 | 4378 | 0.287 | -0.0556 | No | ||
| 10 | PTCH1 | 430278 | 4840 | 0.226 | -0.0761 | No | ||
| 11 | GLI3 | 5690148 | 4997 | 0.207 | -0.0804 | No | ||
| 12 | GLI2 | 3060632 | 6184 | 0.114 | -0.1421 | No | ||
| 13 | MTSS1 | 780435 2370114 | 9419 | 0.021 | -0.3158 | No | ||
| 14 | FBXW11 | 6450632 | 9778 | 0.015 | -0.3348 | No | ||
| 15 | GNAI3 | 4670739 | 9813 | 0.014 | -0.3363 | No | ||
| 16 | XPO1 | 540707 | 11124 | -0.008 | -0.4067 | No | ||
| 17 | AKT1 | 5290746 | 11234 | -0.010 | -0.4124 | No | ||
| 18 | GLI1 | 4560176 | 11450 | -0.014 | -0.4237 | No | ||
| 19 | GNAI1 | 4560390 | 13389 | -0.065 | -0.5268 | No | ||
| 20 | SHH | 5570400 | 13550 | -0.073 | -0.5339 | No | ||
| 21 | SAP18 | 3610092 | 13837 | -0.091 | -0.5476 | No | ||
| 22 | FOXA2 | 540338 5860441 | 14063 | -0.108 | -0.5576 | No | ||
| 23 | CSNK1A1 | 2340427 | 14138 | -0.115 | -0.5593 | No | ||
| 24 | RAB23 | 2970075 | 14246 | -0.127 | -0.5626 | No | ||
| 25 | GNAO1 | 2510292 6590487 | 14267 | -0.129 | -0.5612 | No | ||
| 26 | CSNK1G2 | 3060095 4730037 | 15605 | -0.459 | -0.6242 | No | ||
| 27 | GNG2 | 2230390 | 16115 | -0.675 | -0.6385 | Yes | ||
| 28 | MAP2K1 | 840739 | 16129 | -0.683 | -0.6259 | Yes | ||
| 29 | IFT172 | 3800372 7100400 | 16596 | -0.955 | -0.6324 | Yes | ||
| 30 | SAP30 | 5080735 | 16978 | -1.209 | -0.6293 | Yes | ||
| 31 | RBBP7 | 430113 450450 2370309 | 17109 | -1.334 | -0.6104 | Yes | ||
| 32 | KIF3A | 5050348 6650079 | 17111 | -1.335 | -0.5844 | Yes | ||
| 33 | LGALS3 | 2120239 | 17261 | -1.492 | -0.5634 | Yes | ||
| 34 | CSNK1G3 | 110450 | 17294 | -1.527 | -0.5354 | Yes | ||
| 35 | HDAC1 | 2850670 | 17539 | -1.803 | -0.5134 | Yes | ||
| 36 | PRKCD | 770592 | 17650 | -1.931 | -0.4818 | Yes | ||
| 37 | GNB1 | 2120397 | 17866 | -2.237 | -0.4498 | Yes | ||
| 38 | CSNK1E | 2850347 5050093 6110301 | 17912 | -2.315 | -0.4071 | Yes | ||
| 39 | CREBBP | 5690035 7040050 | 18081 | -2.625 | -0.3651 | Yes | ||
| 40 | GSK3B | 5360348 | 18106 | -2.696 | -0.3139 | Yes | ||
| 41 | PIAS1 | 5340301 | 18332 | -3.281 | -0.2621 | Yes | ||
| 42 | SIN3A | 2190121 | 18531 | -4.292 | -0.1892 | Yes | ||
| 43 | SPOP | 450035 | 18556 | -4.589 | -0.1012 | Yes | ||
| 44 | HDAC2 | 4050433 | 18596 | -5.359 | 0.0011 | Yes |
